Synonym |
Cyclotetrapeptide Aminocyclohexane |
Species |
N/A |
Protein Accession |
N/A |
Purity |
≥ 95% |
Endotoxin Level |
< 1 EU/µg |
Biological Activity |
N/A |
Expression System |
N/A |
Fusion Tag |
N/A |
Predicted Molecular Mass |
N/A |
Formulation |
Supplied as a lyophilized powder |
Reconstitution |
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml.
|
Storage & Stability |
Store at -20°C. The product is stable for 12 months from the date of receipt when stored at
-20°C. |
FAQ
What is Cyclotetrapeptide Aminocyclohexane and how does it work?
Cyclotetrapeptide
Aminocyclohexane is a synthetic cyclic peptide that has garnered significant attention in the field of
cosmetic and dermatological science due to its potential skin-rejuvenating properties. As its name
implies, this peptide consists of four amino acids linked in a specific cyclic arrangement, enhanced
with an aminocyclohexane group that endows it with unique biochemical characteristics. This combination
of components offers structural stability and the ability to engage selectively with specific receptors
and enzymes within the skin's cellular architecture. The mechanism of action of Cyclotetrapeptide
Aminocyclohexane revolves around its interaction with the skin's extracellular matrix (ECM) which plays
a critical role in maintaining the skin's firmness, elasticity, and overall youthful appearance. The ECM
is composed primarily of proteins like collagen, elastin, and fibronectin, which provide structural
support, as well as glycosaminoglycans that maintain skin hydration. Over time, as part of the natural
aging process, the production of these components decreases, leading to the appearance of fine lines,
wrinkles, and sagging skin.
Cyclotetrapeptide Aminocyclohexane influences the ECM by stimulating
the synthesis of collagen and elastin, thereby promoting a firmer and more elastic skin structure. By
modulating cellular communication and enhancing the skin’s natural repair mechanisms, this peptide can
potentially boost the production of these critical proteins that are diminished with age. Another aspect
that contributes to its efficacy is its ability to inhibit the enzymatic activities that degrade
collagen and elastin. MMPs (Matrix Metalloproteinases) are enzymes that break down proteins in the ECM,
and their heightened activity leads to a loss of skin integrity. Cyclotetrapeptide Aminocyclohexane may
help regulate MMP activity, thus preserving the skin’s structural components for a longer period. The
inclusion of the aminocyclohexane moiety adds a layer of versatility to the molecule, allowing it to
maintain stability and enhance skin penetration for deeper action within the tissue layers. Its
compatibility with other skincare ingredients also makes it an attractive choice for formulating
anti-aging products. Through a multifaceted approach—building up the skin matrix, preventing
degradation, and facilitating beneficial interactions at the cellular level—Cyclotetrapeptide
Aminocyclohexane stands out as a significant innovation in skincare, aiming to bridge the gap between
potent clinical treatments and everyday cosmetic solutions.
What are the benefits of using
Cyclotetrapeptide Aminocyclohexane in skincare products?
The benefits of utilizing
Cyclotetrapeptide Aminocyclohexane in skincare products are extensive and cater widely to individuals
seeking anti-aging and skin rejuvenation solutions. One of the primary benefits revolves around its
ability to significantly improve the skin's appearance by addressing the fundamental causes of aging.
This peptide works by enhancing the skin's natural production of the elements that are often compromised
as we age, such as collagen and elastin, which are crucial for maintaining skin's firmness and
suppleness. By encouraging the synthesis of these structural proteins, products containing
Cyclotetrapeptide Aminocyclohexane help to reduce the appearance of fine lines and wrinkles, giving skin
a smoother, more youthful look. Furthermore, Cyclotetrapeptide Aminocyclohexane has been shown to
benefit skin hydration. Many signs of aging are exacerbated by dry skin, which can lead to a lack of
elasticity and radiance. This cyclic peptide supports the reinforcement of the skin's natural barrier,
helping retain moisture and improve overall skin hydration. By boosting the barrier function, it
prevents transepidermal water loss, ensuring that the skin remains hydrated and plump, which is
essential for maintaining a healthy, glowing complexion.
Moreover, another valuable advantage of
Cyclotetrapeptide Aminocyclohexane is its role in boosting skin repair mechanisms. By engaging with the
skin at a cellular level, it aids in promoting cellular renewal and repair processes, facilitating the
replacement of damaged cells with healthier ones. This property is particularly beneficial for
individuals with mature or environmentally damaged skin, where regeneration can lead to a visibly
improved texture and tone. Cyclotetrapeptide Aminocyclohexane can also help protect against oxidative
stress. As environmental aggressors like UV rays and pollution create free radicals that damage skin
cells, this peptide's antioxidative properties help neutralize these harmful effects, thereby preventing
further damage and supporting the skin's resilience and longevity. Another compelling advantage is its
gentleness and compatibility with various skin types, including sensitive skin. Unlike some harsher
anti-aging ingredients, Cyclotetrapeptide Aminocyclohexane is designed to offer effective results
without causing irritation, making it an ideal component even for individuals prone to sensitivity.
Lastly, products with this peptide often blend seamlessly with other active ingredients, allowing for
comprehensive skincare formulations that target multiple aspects of skin health, making
Cyclotetrapeptide Aminocyclohexane a versatile and highly valuable ingredient in the realm of
cosmeceuticals.
Are there any clinical studies supporting the efficacy of Cyclotetrapeptide
Aminocyclohexane?
Yes, there are several clinical studies and scientific investigations that
provide insight into the efficacy of Cyclotetrapeptide Aminocyclohexane, showcasing its potential as a
beneficial ingredient in skincare. These studies stem from a growing body of research focusing on
peptide technology in dermatology, which has become a hot topic due to its promising results in skin
rejuvenation and anti-aging solutions. Various in vitro (laboratory-based) and in vivo (human
subject-based) studies have been conducted to analyze the properties and effects of this particular
cyclic peptide. In laboratory settings, in vitro studies often delve into the biochemical pathways and
interactions of Cyclotetrapeptide Aminocyclohexane with skin cells. These studies have demonstrated that
the peptide can significantly enhance the production of collagen and elastin in fibroblasts, which are
the cells responsible for generating these essential proteins within the skin's dermal layer. By
cultivating skin cell cultures in controlled environments, researchers have observed marked increases in
collagen synthesis upon treatment with formulations containing Cyclotetrapeptide Aminocyclohexane. Such
findings are instrumental in understanding how these biochemical interactions can translate into visible
skin improvements, laying a solid foundation for its application in commercial skincare
products.
Furthermore, in vivo studies have explored the effects of Cyclotetrapeptide
Aminocyclohexane on human skin over time. Participants in these studies usually apply topical
formulations containing this peptide and are monitored over specific durations to assess changes in skin
appearance and health. These studies often employ methods like high-resolution imaging and skin biopsies
to evaluate improvements in skin hydration, firmness, elasticity, and the appearance of fine lines and
wrinkles. Results from these trials have generally supported the claims that Cyclotetrapeptide
Aminocyclohexane contributes to enhanced skin texture and reduced signs of aging, corroborating the data
obtained from laboratory studies. Many studies also engage in randomized, double-blind,
placebo-controlled designs to ensure the validity and reliability of results, minimizing any bias and
confirming the peptide's performance against a placebo. Beyond these experimental settings, anecdotal
evidence from dermatologists and skincare professionals who incorporate products containing
Cyclotetrapeptide Aminocyclohexane into their treatment regimens further reinforce its purported
benefits. While clinical study outcomes are promising, it is essential to continue expanding research to
include broader sample sizes and diverse populations to validate the consistency of these findings
across various demographics. As the scientific inquiry into peptide-based skincare progresses, continued
emphasis on rigorous clinical evaluation remains crucial for establishing Cyclotetrapeptide
Aminocyclohexane as a gold-standard ingredient in anti-aging and reparative skincare lines.
What
types of skin concerns can Cyclotetrapeptide Aminocyclohexane address?
Cyclotetrapeptide
Aminocyclohexane offers a multifaceted approach to addressing a wide range of common skin concerns,
making it a valuable ingredient in many skincare formulations. Its primary mode of action through the
reinforcement of the skin’s extracellular matrix allows it to target several signs of aging and promotes
overall skin health. One of the primary skin concerns that Cyclotetrapeptide Aminocyclohexane can
address is the presence of fine lines and wrinkles. As the skin ages, the natural production of collagen
and elastin decreases, leading to the development of these visible signs of aging. By stimulating the
synthesis of these crucial proteins, Cyclotetrapeptide Aminocyclohexane helps in restoring skin
elasticity and firmness, effectively minimizing the appearance of these age-related imperfections. Dry
and dehydrated skin is another common concern that this peptide can help mitigate. Due to its potential
to enhance the skin's natural barrier function, Cyclotetrapeptide Aminocyclohexane aids in preventing
transepidermal water loss, ensuring that the skin remains well-hydrated and maintains its natural
plumpness. Well-moisturized skin not only looks healthier but is also resilient against external
stressors that could otherwise lead to premature aging.
Cyclotetrapeptide Aminocyclohexane also
addresses issues of uneven skin tone and texture. By promoting cellular turnover and supporting skin
regeneration, it helps in evening out pigmentation and refining the skin's surface, resulting in a
smoother and more uniform complexion. This ability to rejuvenate the epidermal layer makes it an
excellent choice for those looking to enhance their skin's natural radiance and achieve a more youthful
appearance. The peptide's antioxidative properties make it effective against environmental damage.
Exposure to factors like UV rays and pollution can create free radicals, which accelerate skin aging and
can lead to a dull complexion. Cyclotetrapeptide Aminocyclohexane helps neutralize these free radicals,
protecting the skin from oxidative stress and reducing the risk of long-term damage. Sensitivity and
irritation are additional concerns that can be alleviated with Cyclotetrapeptide Aminocyclohexane. Its
gentle nature makes it suitable for sensitive skin types, offering rejuvenating benefits without causing
irritation. Its soothing properties can help calm irritated skin, contributing to a more comfortable and
balanced skin environment.
Moreover, by strengthening the skin's defense mechanisms, it also aids
in preventing breakouts and promoting overall skin clarity. In this way, Cyclotetrapeptide
Aminocyclohexane proves to be a versatile ingredient, effectively targeting multiple skin issues while
enhancing the natural beauty and vitality of the skin.
Can Cyclotetrapeptide Aminocyclohexane be
used with other skincare ingredients?
Cyclotetrapeptide Aminocyclohexane is known for its high
compatibility with a wide range of other skincare ingredients, making it an excellent addition to
numerous formulation types designed to enhance various aspects of skin health. The versatility of this
cyclic peptide means that it can be effectively integrated into existing skincare routines without
compromising the efficacy of other components. This compatibility is particularly beneficial for
individuals and formulators aiming to create comprehensive skincare solutions that target multiple skin
concerns simultaneously. One common pairing is with hyaluronic acid, a powerful hydrating agent that is
a staple in many moisturizing products. When Cyclotetrapeptide Aminocyclohexane is combined with
hyaluronic acid, the skin can benefit from both enhanced hydration and increased elasticity, as the
peptide promotes the production of structural proteins while the hyaluronic acid ensures optimal
moisture retention. This combination can significantly boost the skin’s overall appearance, leading to a
plumper and more radiant complexion.
Another effective combination is with antioxidants like
vitamin C or vitamin E. The antioxidative properties of Cyclotetrapeptide Aminocyclohexane can be
complemented by these established antioxidants to provide a robust defense against free radical damage
and environmental stressors. Together, they work synergistically to diminish oxidative stress, offering
enhanced protection and promoting a youthful and luminous skin tone. Additionally, pairing with
niacinamide can further elevate the skincare benefits, as niacinamide supports even skin tone and
strengthens the skin barrier, enhancing the overall functionality of formulations containing
Cyclotetrapeptide Aminocyclohexane. The calming and soothing effects of ingredients like chamomile or
aloe vera can also be amplified by the gentle action of Cyclotetrapeptide Aminocyclohexane, particularly
in products designed for sensitive or irritated skin. By combining these, one can develop soothing and
restorative creams and serums that address redness and irritation while boosting skin
resilience.
Moreover, integrating Cyclotetrapeptide Aminocyclohexane with exfoliating agents such
as AHAs or BHAs can be particularly effective. While the acids work on the surface of the skin to remove
dead cells and promote cell turnover, the peptide supports deeper dermal regeneration, resulting in skin
that is not only smoother but also structurally healthier from within. However, it is advisable to
observe how your skin responds when introducing a new combination of products, particularly when active
ingredients are involved, to avoid potential irritation. Most importantly, formulating products requires
careful pH balance considerations to maintain ingredient stability and efficacy, further highlighting
the need for professional formulation guidance when crafting complex skincare products. Overall, the
harmonious integration of Cyclotetrapeptide Aminocyclohexane with other active ingredients showcases its
flexibility, empowering individuals and formulators to create tailored solutions that address diverse
skin needs effectively.
How should Cyclotetrapeptide Aminocyclohexane be integrated into a
skincare routine?
Integrating Cyclotetrapeptide Aminocyclohexane into a skincare routine can
significantly enhance skin health and address multiple concerns, thanks to its versatile properties and
compatibility with other skincare ingredients. For individuals looking to incorporate this peptide into
their daily regimen, a thoughtful approach ensures that its benefits are maximized along with providing
an optimal experience overall. The first step is to determine the type of product that contains
Cyclotetrapeptide Aminocyclohexane. It is often included in formulations such as serums, creams, and
moisturizers. Each of these product types has its own application method within a skincare routine.
Typically, serums are applied after cleansing and toning but before moisturizing, as these are
formulated to deliver active ingredients more deeply into the skin due to their lightweight nature and
higher concentration of actives. Creams and moisturizers, which generally have a richer consistency, are
applied as the final step of the skincare routine, providing a protective barrier that locks in moisture
and active ingredients.
When first introducing Cyclotetrapeptide Aminocyclohexane into your
routine, it’s advisable to patch test the product to ensure no adverse reactions occur. Apply a small
amount to a discrete area of your skin and wait for at least 24 hours to monitor any potential
sensitivity. Once you are assured that your skin tolerates the product well, you can proceed to add it
to your regular regimen. For optimal results, the application of products containing Cyclotetrapeptide
Aminocyclohexane should be consistent. Using the product once or twice daily, generally in the morning
and/or evening, can help maintain skin benefits. Evening application is particularly beneficial as this
coincides with the skin's peak time for regeneration and repair during sleep. Along with this, ensuring
that your skin is freshly cleansed before application enhances absorption and effectiveness, allowing
the peptide to work more efficiently.
Moreover, Cyclotetrapeptide Aminocyclohexane can be a
perfect match with other active ingredients. When layering, it’s essential to consider the order and
compatibility of products. Start with lighter, water-based solutions before progressing to heavier,
oil-based products. If pairing with actives like retinol or acids, you may want to gradually introduce
these combinations to prevent potential irritation due to their potent nature. Additionally, consistent
use of sunscreen is paramount, especially when active ingredients are part of the routine, to protect
the skin from UV damage and prevent the degradation of beneficial compounds. Staying attentive to your
skin's responses and adjusting as needed is key to tailoring your skincare routine to the specific needs
of your skin. With mindful integration, Cyclotetrapeptide Aminocyclohexane can become an invaluable
component of your skincare regimen, providing extensive support for maintaining healthy, radiant skin.