Synonym |
Pantothenoyl Dipeptide |
Species |
Human |
Protein Accession |
NA |
Purity |
Greater than 95% |
Endotoxin Level |
< 1.0 EU per 1 μg of protein |
Biological Activity |
NA |
Expression System |
E. coli |
Fusion Tag |
NA |
Predicted Molecular Mass |
NA |
Formulation |
Supplied as a lyophilized powder |
Reconstitution |
Centrifuge vial before opening. Reconstitute in sterile deionized water to a concentration of
0.1-1.0 mg/mL. |
Storage & Stability |
Store at -20°C. Prolonged storage at -20°C should be avoided. Reconstituted protein should be
stored at 4°C for up to one week. |
FAQ
What is Pantothenoyl Dipeptide and how does it work in skincare?
Pantothenoyl Dipeptide is a
revolutionary ingredient in the skincare industry, utilized for its remarkable ability to enhance skin
health and appearance. It is a compound derived from a combination of pantothenic acid (vitamin B5) and
a dipeptide, which together work synergistically to offer both reparative and protective benefits for
the skin. This unique combination makes Pantothenoyl Dipeptide exceptionally effective at improving skin
texture, reducing signs of aging, and enhancing overall skin barrier function.
When incorporated
into skincare products, Pantothenoyl Dipeptide penetrates deep into the skin layers. Here, it works at a
cellular level to stimulate the natural production of collagen and elastin, two vital proteins that are
crucial for maintaining skin firmness and elasticity. This stimulation helps to reduce the appearance of
fine lines and wrinkles, giving the skin a youthful and plump appearance. Moreover, this ingredient aids
in the reduction of transepidermal water loss, thereby keeping the skin hydrated and supple. Its
hydrating properties are further enhanced by its interaction with other moisturizing agents within
skincare formulations, ensuring prolonged moisture retention.
Additionally, Pantothenoyl
Dipeptide possesses powerful antioxidant properties. It neutralizes free radicals—unstable molecules
that damage the skin's cellular structure and accelerate aging. By protecting the skin from oxidative
stress, it prevents premature aging and enhances skin resilience against environmental aggressors such
as pollution and UV radiation. Furthermore, its anti-inflammatory properties help soothe irritated skin,
reducing redness and sensitivity, making it suitable for a variety of skin types, including sensitive
and acne-prone skin.
In essence, Pantothenoyl Dipeptide is a multifunctional skincare hero that
addresses a multitude of skin concerns. Whether you are dealing with aging skin, dehydration, or skin
sensitivity, this ingredient offers a comprehensive solution, making it a must-have in any advanced
skincare routine.
What are the benefits of using products with Pantothenoyl Dipeptide for
anti-aging purposes?
Products containing Pantothenoyl Dipeptide offer a host of benefits
specifically tailored to combat the visible signs of aging, making them an excellent choice for anyone
looking to enhance their anti-aging skincare regime. One of the primary benefits of Pantothenoyl
Dipeptide is its exceptional ability to promote collagen synthesis. Collagen is a key structural protein
that provides the skin with firmness and elasticity. As we age, the natural production of collagen slows
down, leading to the formation of wrinkles and sagging skin. Pantothenoyl Dipeptide works by stimulating
fibroblasts, the cells responsible for collagen production, thereby boosting collagen levels and helping
to restore youthful skin structure.
Additionally, Pantothenoyl Dipeptide enhances the skin's
natural repair processes, accelerating the healing of damaged tissues and regeneration of healthy skin
cells. This reparative action not only addresses existing signs of aging but also provides a
preventative effect by fortifying the skin's resilience and delay the onset of future lines and
wrinkles. The combination of repair and prevention makes products with Pantothenoyl Dipeptide uniquely
effective as an anti-aging solution.
Furthermore, this active ingredient plays a crucial role in
maintaining skin hydration levels. With age, the skin's ability to retain moisture diminishes, resulting
in dryness and an accentuated appearance of aging signs. By reducing transepidermal water loss and
attracting moisture to the skin, Pantothenoyl Dipeptide ensures that skin remains hydrated, plump, and
smooth. Well-hydrated skin is more elastic and resilient, further contributing to a reduction in the
visibility of aging signs.
Antioxidant protection is another significant benefit of using
Pantothenoyl Dipeptide in anti-aging formulations. It combats oxidative stress caused by environmental
factors like UV radiation and pollution—factors known to accelerate skin aging. By neutralizing free
radicals, Pantothenoyl Dipeptide prevents and repairs damage, contributing to healthier, younger-looking
skin.
Ultimately, the comprehensive anti-aging benefits of Pantothenoyl Dipeptide make it an
invaluable addition to skincare products focused on preserving and enhancing skin vitality, offering
both immediate improvements and long-term results in the fight against aging.
Is Pantothenoyl
Dipeptide suitable for all skin types, including sensitive skin?
Pantothenoyl Dipeptide is known
for its versatility and effectiveness across various skin types, making it a valuable addition to
skincare products designed to cater to diverse customer needs. One of the standout features of
Pantothenoyl Dipeptide is its compatibility with sensitive skin. Individuals with sensitive skin often
face challenges when choosing skincare products due to the risk of irritation and adverse reactions.
However, Pantothenoyl Dipeptide offers soothing benefits that diminish the risk of irritation, redness,
and inflammation, creating a calming and nurturing effect on the skin.
The ingredient’s
anti-inflammatory properties make it particularly suitable for sensitive skin, as it works to reduce
redness and calm inflamed or reactive areas. Furthermore, it strengthens the skin's barrier, fortifying
its natural defenses against environmental stressors. A healthy barrier is crucial for sensitive skin
since it reduces reactivity and prevents moisture loss, leading to softer and more resilient skin over
time.
Pantothenoyl Dipeptide is also highly beneficial for those with dry or dehydrated skin. Its
ability to lock in moisture helps to mitigate dryness, making the skin feel comfortable and hydrated. By
improving moisture retention, this ingredient alleviates dryness-associated discomfort, resulting in
smoother, more supple skin.
For those with oily or acne-prone skin, Pantothenoyl Dipeptide is
non-comedogenic, meaning it does not clog pores or aggravate acne. On the contrary, its
anti-inflammatory action can help reduce acne-related redness and swelling, promoting a clearer
complexion. Moreover, its lightweight nature ensures it feels comfortable even on oily skin, absorbing
quickly without leaving a greasy residue.
Normal and combination skin types also benefit from the
equilibrating nature of Pantothenoyl Dipeptide, which balances oil production while ensuring adequate
hydration in drier areas. It supports overall skin health and vitality without disrupting the natural
balance that these skin types strive to maintain.
By providing tailored benefits to each skin
type while minimizing the risk of adverse reactions, Pantothenoyl Dipeptide stands out as a universally
suitable ingredient that enhances skincare efficacy across the board.
How does Pantothenoyl
Dipeptide enhance skin hydration and barrier function?
Pantothenoyl Dipeptide plays a crucial
role in boosting skin hydration and improving the integrity of the skin's barrier, two fundamental
aspects of maintaining healthy, resilient skin. Its mechanism of action is multi-faceted, providing deep
hydration while simultaneously enhancing the skin's natural defenses.
One of the primary ways
Pantothenoyl Dipeptide enhances skin hydration is by reducing transepidermal water loss (TEWL). TEWL
occurs when moisture evaporates from the skin's surface, leading to dryness and dehydration. By
reinforcing the lipid matrix that constitutes the skin’s barrier, Pantothenoyl Dipeptide decreases the
rate of moisture loss, ensuring that the skin retains adequate levels of hydration. This results in skin
that feels supple, soft, and comfortable.
In addition, Pantothenoyl Dipeptide attracts water
molecules from the surrounding environment and binds them to the skin cells, maximizing moisture
retention. This hydrating property makes it particularly beneficial in skincare formulations aimed at
combating dryness and promoting long-lasting moisturization. When used consistently, products containing
Pantothenoyl Dipeptide help maintain the skin's optimal hydration levels, preventing the appearance of
dryness-induced imperfections such as flakiness or roughness.
The strengthening of the skin's
barrier function by Pantothenoyl Dipeptide further supports its hydrating benefits. A robust barrier is
crucial as it serves as the first line of defense against environmental aggressors, allergens, and
pathogens. By enhancing the production of barrier lipids and proteins, Pantothenoyl Dipeptide fortifies
the skin structure, making it less susceptible to external irritants. This bolstered barrier means that
the skin is better equipped to retain moisture and resist external challenges, directly translating into
a healthier appearance.
Enhanced barrier function also has a protective impact on skin hydration;
when the barrier is intact, the skin is more efficient in repelling harsh environmental factors while
retaining the essential moisture needed for its repair and regeneration processes. Altogether,
Pantothenoyl Dipeptide's ability to both hydrate the skin and reinforce its natural defenses makes it an
essential ingredient for maintaining vibrant, resilient skin.
Can Pantothenoyl Dipeptide help
with skin redness and irritation?
Pantothenoyl Dipeptide is notably effective in alleviating skin
redness and irritation, making it a highly prized ingredient in the formulation of skincare products for
sensitive and irritated skin. Thanks to its unique composition, Pantothenoyl Dipeptide provides both
soothing and repairing benefits that help restore skin to a more balanced and calm state.
One of
the primary mechanisms through which Pantothenoyl Dipeptide alleviates redness and irritation is its
potent anti-inflammatory action. Inflammation is a skin defense process that, while essential, can lead
to visible redness and discomfort when overstimulated. By suppressing the inflammatory pathways and
calming hyperactive immune responses in the skin, Pantothenoyl Dipeptide effectively diminishes both
visible redness and associated irritation. This soothing effect not only targets acute issues but also
aids in preventing recurrent flare-ups often experienced by those with sensitive skin.
In
addition to its anti-inflammatory benefits, Pantothenoyl Dipeptide enhances the skin's natural barrier
function, which plays a critical role in managing irritation. A compromised barrier allows external
irritants, such as pollutants, allergens, or harsh climate conditions, to penetrate more readily,
triggering inflammation and irritation. Pantothenoyl Dipeptide works to reinforce the barrier, improving
its structural integrity and ability to resist such irritants. By fortifying the skin's defenses, it
reduces susceptibility to environmental stressors, thereby minimizing the potential for irritation and
redness.
Moreover, Pantothenoyl Dipeptide promotes skin healing and repair. When irritation or
redness occur, damage at the cellular level can ensue, exacerbating skin sensitivity and creating a
cycle of irritation. By supporting cell renewal and repair processes, Pantothenoyl Dipeptide assists in
restoring optimal skin health, ensuring that the skin becomes more resilient over time. The enhanced
skin repair aids in reducing the duration and severity of irritation episodes.
Therefore,
products formulated with Pantothenoyl Dipeptide offer a comprehensive approach to managing redness and
irritation, striking the right balance between calming immediate symptoms and strengthening the skin for
long-term resilience.