Synonym |
AAA-NH2 |
Species |
Not applicable |
Protein Accession |
C9H19ClN4O3 |
Purity |
Greater than 95% as determined by SDS-PAGE |
Endotoxin Level |
Less than 1 EU/ug |
Biological Activity |
Not determined |
Expression System |
Not determined |
Fusion Tag |
Not applicable |
Predicted Molecular Mass |
79955 Da |
Formulation |
Lyophilized from a 0.2 μm filtered solution in PBS. |
Reconstitution |
Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of
0.1-1.0 mg/ml. |
Storage & Stability |
Store at -20°C. Avoid repeated freeze-thaw cycles. |
FAQ
What is AAA-NH2 C9H19ClN4O3 (CAS 79955-53-6) used for in scientific research?
AAA-NH2 C9H19ClN4O3 is
a specialized compound utilized in various areas of scientific research that require the application of
complex chemical compounds. This particular chemical is noted for its versatility and effectiveness in
binding assays and enzymatic studies. In biochemical research, it serves to further understand
biochemical pathways and mechanisms that are essential in comprehensive studies of cellular processes
and reactions. Its structure, comprising amino groups and a chlorine ion, is integral in its function as
it enables the compound to participate in specific interactions with biomolecules, making it invaluable
in the study of protein expression, interactions, and the synthesis of various biomolecular complexes.
Researchers value its role in assay developments, particularly where high specificity and affinity are
required. Additionally, it can be instrumental in pharmacological studies, where elucidating
drug-receptor interactions is critical. Due to these applications, AAA-NH2 is often handled in
pharmaceutical research and development laboratories aiming to discover new drug targets or improve
existing therapeutic agents. Given the complexity and precise nature of research it supports, this
compound provides researchers with the data needed to explore new hypotheses, especially in the field of
drug discovery and development involving peptidomimetic molecules. Its unique structure allows
scientists to explore its role as a chemical building block with the potential to foster innovation in
synthetic methodologies or in the design of new experimental procedures. The reactivity patterns
provided by this compound are frequently leveraged to simulate conditions that mimic physiological
settings, thus offering a predictive glimpse into how new therapeutic agents might perform in biological
systems. Overall, its wide-ranging applications in scientific research make AAA-NH2 C9H19ClN4O3 a
compound of choice for numerous cutting-edge research projects.
How does AAA-NH2 C9H19ClN4O3
contribute to advancements in pharmaceutical research?
The role of AAA-NH2 C9H19ClN4O3 in
pharmaceutical research is quite significant due to its contributions in pushing the boundaries of
what's possible in drug development and medicinal chemistry. This compound, thanks to its specific
molecular structure, is of considerable interest for its role in the exploration of therapeutic
interventions and the calibration of biochemical assays enhancing the understanding of disease
mechanisms. In pharmaceutical research, AAA-NH2's unique properties make it a pivotal component in the
design and synthesis of peptidomimetic drugs. Such drugs mimic the structures of natural peptides,
providing the possibility of more stable and effective therapeutic agents. By incorporating AAA-NH2 into
drug development processes, researchers strive to create medications that offer greater efficacy,
reduced side effects, and improved pharmacokinetic profiles. Researchers find great promise in utilizing
this compound to improve the selectivity and potency of new drugs aimed at challenging targets, such as
those expressed in complex diseases like cancer or autoimmune disorders. Beyond synthesis and drug
development, AAA-NH2 is crucial in the nuanced study of drug efficacy and safety. It serves as a model
to simulate potential physiological interactions, thereby predicting possible outcomes of therapeutic
agents within the body. Researchers employ AAA-NH2 in pharmacokinetics and pharmacodynamics studies to
ascertain optimal dosages and delivery methods, hoping to maximize therapeutic benefits while minimizing
adverse effects. In addition to these traditional roles, AAA-NH2 is increasingly being explored in
innovative pharmaceutical technologies such as targeted drug delivery systems and smart drug designs,
which rely heavily on the precision these molecules offer. The ongoing exploration and validation of
AAA-NH2 in bench-to-bedside translational research highlight its continued importance in redefining
pharmaceutical care and therapy. Therefore, this compound acts not just as a fundamental building block
in synthetic drug chemistry but also as a critical tool paving the way for future breakthroughs in
medical science.
In what ways does AAA-NH2 C9H19ClN4O3 enhance biochemical assay performance?
AAA-NH2 C9H19ClN4O3 significantly enhances biochemical assay performance primarily due to its
specificity, reactivity, and stability, all of which are crucial parameters in scientific research
protocols that require reliable and consistent results. Its chemical structure allows it to act as an
ideal candidate for many assay types, primarily where target binding and detection sensitivity are
required. One of the foremost benefits of AAA-NH2 in assay enhancement is its ability to participate in
high-affinity binding interactions with proteins, nucleic acids, and other compounds, increasing the
sensitivity of detection in assays and leading to more definitive and interpretable results. This is
particularly useful in enzyme-linked immunosorbent assays (ELISA), fluorescence resonance energy
transfer (FRET) assays, and other similar biochemical techniques, where the detection of low-abundance
biomolecules can be a formidable challenge. AAA-NH2's role doesn’t stop at binding; it is instrumental
in optimizing assay conditions to improve the reaction rates and stability of the assay components. Its
resistance to degradation enables assays to retain their integrity over longer investigative periods,
thereby allowing extended testing regimes without losing fidelity. Moreover, its ability to contribute
to reproducibility makes it desirable for high throughput screenings in drug discovery processes, where
hundreds or even thousands of compounds are tested, saving time and resources. Also, AAA-NH2 facilitates
the easy labeling of biomolecules with minimal interference with their native functions, an aspect
crucial in live-cell imaging and kinetic studies of biomolecular interactions. Its water solubility and
ease of conjugation empower researchers to execute theoretical experiment designs practically, providing
versatility across various assay formats. Additionally, the compound’s capacity to fine-tune the
physical and chemical conditions of an assay system makes it a powerful tool for researchers aiming to
detect and quantify molecular interactions with precision. This optimization capability enhances the
overall performance of biochemical assays by enhancing accuracy, sensitivity, and reliability, thus
offering significant contributions to advancing research methodologies.
Can AAA-NH2 C9H19ClN4O3
be used in structural biology?
Indeed, AAA-NH2 C9H19ClN4O3 holds considerable potential for
applications in structural biology, an important scientific discipline focused on elucidating the
three-dimensional structures of biological macromolecules. Understanding these molecular architectures
is crucial because the function of biological molecules, such as proteins and nucleic acids, is deeply
tied to their shapes, configurations, and interactions within a cell. AAA-NH2 can be deployed in
structural biology as a labeling agent due to its functional groups, which facilitate binding to target
molecules without significantly altering their structures. Such modifications allow it to act as a
beacon or marker within various analytical techniques like X-ray crystallography, NMR spectroscopy, and
cryo-electron microscopy. In these roles, AAA-NH2 aids in visualizing molecular structures and mapping
conformational changes, which are essential for understanding protein folding, dynamics, and
interactions.
Additionally, this compound can be strategically used in cross-linking experiments.
Here it helps create covalent bonds between interacting protein partners, capturing transient
interactions that are often difficult to study. By stabilizing these interactions, AAA-NH2 enables
researchers to isolate complex structures for further studies, uncovering insights into how proteins
operate within larger molecular assemblies and pathways. Furthermore, it contributes to the development
of biomolecular models and simulations, offering a data-rich platform for testing hypotheses about
molecular motion and interaction under varying physiological conditions. It is also applicable in
docking studies, where the details of how a drug or molecule interacts with its target site on a protein
are examined, a critical component of rational drug design efforts. The data generated when using
AAA-NH2 in these structural studies not only provide valuable insights into the fundamental aspects of
biology but also pave the way for new therapeutic strategies in medicine. By expanding our understanding
of how biological macromolecules are organized and function at the atomic level, AAA-NH2 significantly
enriches the toolbox available for structural biology research.
What safety considerations should
researchers keep in mind when handling AAA-NH2 C9H19ClN4O3?
When handling AAA-NH2 C9H19ClN4O3,
researchers must be meticulous in observing safety protocols given the complex nature and chemical
properties associated with this compound. Ensuring a safe working environment is crucial to prevent any
potential exposure risks that could arise during its handling, storage, or transportation. First,
researchers should conduct a comprehensive risk assessment of the potential hazards associated with
AAA-NH2 prior to its use in laboratory settings, taking into account the specific procedures,
concentrations, and quantities used. Personal protective equipment (PPE) is another critical component
of safety and must include lab coats, appropriate gloves, and safety goggles to prevent any direct
contact with the skin or eyes, which could result in irritation or a chemical reaction. Additionally,
working in a fume hood is advisable as it minimizes inhalation risks and provides an enclosed
environment to manage any spills or accidental releases, ensuring laboratory ventilation systems reduce
potential airborne contamination. Since AAA-NH2 may pose specific health risks if ingested or improperly
inhaled, strict hygiene protocols are mandatory; these include washing hands thoroughly after handling
and avoiding eating or drinking in areas where the compound is in use. Workshop technical training
should be provided regularly so that all team members are up-to-date with emergency procedures, such as
spill kits usage or first aid measures should accidental exposure occur. Proper storage is also a key
factor for maintaining safety; researchers should ensure the chemical is stored in a well-ventilated,
temperature-controlled environment away from incompatible substances, such as oxidizing agents, that
could trigger unintended reactions. Accurate labeling and inventory management are essential to avoid
mix-ups and to manage stock levels effectively. Furthermore, waste disposal of AAA-NH2 must comply with
institutional guidelines and regulatory requirements to prevent any environmental contamination,
involving skilled personnel who understand how to neutralize and discard hazardous chemicals
responsibly. Training sessions regarding the safety data sheets (SDS) specific to AAA-NH2 should be
conducted, ensuring that at all times, laboratory personnel are fully informed on the appropriate
measures and the potential risks associated with the research applications of this compound.