Taiy Chemical
Biotinyl-Substance P
Synonym Biotinylated Substance P
Species Human
Protein Accession P20366
Purity ≥ 95%
Endotoxin Level < 1 EU per μg
Biological Activity Fully biologically active when compared to standard
Expression System E. coli
Fusion Tag His Tag
Predicted Molecular Mass 1 kDa
Formulation Lyophilized from a 0.2 μm filtered solution in PBS
Reconstitution Reconstitute in water to a concentration of 0.1-1.0 mg/ml
Storage & Stability Store at -80°C. Avoid repeated freeze-thaw cycles
FAQ
What is Biotinyl-Substance P and how does it work in skincare?

Biotinyl-Substance P is a revolutionary complex used in skincare, celebrated for its potential benefits in enhancing skin vitality and appearance. Essentially, it is a hybrid molecule made by conjugating Biotin, a well-known vitamin, with Substance P, a neuropeptide. Biotin, also known as Vitamin B7 or H, is crucial for the body's keratin infrastructure, supporting healthy skin, hair, and nails. In skincare, Biotin is prized for its replenishing and moisturizing capabilities, thanks to its role in cellular growth and renewal. Substance P, on the other hand, is a neuropeptide involved in various cellular processes, including inflammation and healing. It's recognized for its role in pain perception and its effects on blood flow and tissue nutrition.

When these two potent components are combined into Biotinyl-Substance P, they synergistically work to target epidermal health and function. The presence of Biotin supports cellular rejuvenation, providing the necessary building blocks for skin repair. This can lead to a fortified skin barrier with improved moisture retention, resulting in a plumper and more hydrated texture. Concurrently, the inclusion of Substance P aids in stimulating skin microcirculation, which can be particularly beneficial for dull or compromised skin appearances. Enhanced circulation ensures that skin cells receive the nutrients and oxygen required for optimal functioning, thereby promoting a more radiant and youthful appearance.

Furthermore, Biotinyl-Substance P may also play a role in managing inflammatory responses due to its neuropeptide component. While pure Substance P can be pro-inflammatory, its nuanced application in a controlled skincare matrix has suggested potential benefits in modulating skin sensitivity and discomfort caused by environmental stressors. This balancing act can promote a healthier skin environment, potentially reducing the occurrence of inflammatory lesions such as acne. Skin afflicted by redness or irritation might also find relief with ingredients that cater to enhancing skin resilience, like Biotinyl-Substance P.

Incorporating Biotinyl-Substance P into a skincare regimen is generally aimed at those seeking to improve overall skin texture, firmness, and youthful appearance. It's often found in formulations intended for anti-aging benefits or products targeting compromised skin, offering a multi-faceted approach to skin wellness. As with any active ingredient, it is advisable to perform a patch test before widespread application to ensure compatibility with one’s individual skin type.

Are there any specific skin types or conditions that benefit most from Biotinyl-Substance P?

Biotinyl-Substance P is a versatile ingredient that can benefit a wide range of skin types but is particularly advantageous for certain skin conditions due to its unique properties. Individuals with mature or aging skin stand to gain significantly from incorporating Biotinyl-Substance P into their skincare regimen. As we age, the skin’s natural regenerative processes slow down, leading to a decrease in cell turnover and collagen production, and ultimately resulting in fine lines, wrinkles, and a loss of elasticity. Biotinyl-Substance P can support the rejuvenation of mature skin by promoting cell regeneration and enhancing moisture retention, which helps to firm and plump the skin, making it appear more youthful.

Those with dry or dehydrated skin also can experience benefits from Biotinyl-Substance P. Its moisturizing properties and ability to bolster the skin barrier make it a powerful ingredient for improving hydration, thereby helping the skin retain moisture more effectively. For individuals with dry skin, the improvement in hydration levels can lead to a smoother, softer, and more even texture, reducing flaky patches and improving overall skin health.

Biotinyl-Substance P may also be beneficial for sensitive skin types, particularly those prone to redness and irritation. The anti-inflammatory capabilities stemming from the neuropeptide component of Biotinyl-Substance P can help in soothing and calming irritated skin. This makes it a valuable ingredient for individuals with skin conditions such as rosacea or eczema, who often require skincare solutions that address sensitivity and promote a more resilient skin barrier.

For people experiencing dull or sallow skin, Biotinyl-Substance P may enhance skin radiance through its influence on microcirculation. Improved blood flow and nutrient delivery to the skin cells are crucial for boosting skin’s vitality and bringing back a natural glow. This can be especially beneficial for individuals who feel their skin lacks luster due to environmental stressors or lifestyle factors like fatigue or pollution.

However, while Biotinyl-Substance P can offer considerable benefits for various skin issues, it's important for users with acne-prone or very oily skin to use it with caution. The ingredient might be too rich, potentially exacerbating oiliness or contributing to clogged pores if not formulated appropriately within a product. For such skin types, formulations that include Biotinyl-Substance P along with balancing or clarifying agents might be more suitable.

Ultimately, while Biotinyl-Substance P can be a potent addition to many skincare routines, it is always recommended to tailor skincare practices to one’s specific skin needs and concerns. Consultation with a dermatologist is advised to ascertain whether products featuring Biotinyl-Substance P are appropriate given one's unique skin condition and overall care goals.

Do any side effects or interactions exist for Biotinyl-Substance P in skincare?

While Biotinyl-Substance P is widely regarded as a beneficial ingredient in skincare formulations, users should always exercise caution and conduct thorough research to ensure it is suitable for their personal needs. Generally, Biotinyl-Substance P is considered safe for use in cosmetic products, and adverse reactions are relatively rare when used as directed. However, like with any active skincare ingredient, there may be potential side effects and interactions that some individuals could experience based on their unique skin type and sensitivity levels.

For individuals with highly sensitive skin, the introduction of any new ingredient, including Biotinyl-Substance P, can pose the risk of irritation or allergic reaction. Redness, itching, or a burning sensation following the application of a product containing this compound may indicate an adverse reaction. It is crucial for users, especially those with sensitive or compromised skin, to perform a patch test before incorporating Biotinyl-Substance P into their daily regimen. This can typically be done by applying a small amount of the product to an inconspicuous area of the skin and monitoring for any signs of irritation over 24 to 48 hours.

Biotinyl-Substance P should also be used with care in conjunction with other strong active ingredients, such as exfoliating acids (AHAs, BHAs), retinoids, or Vitamin C. The concurrent use of these products can sometimes result in heightened skin sensitivity or irritation. As Biotinyl-Substance P works to enhance skin hydration and support cell function, its combined use with potent actives should be introduced gradually to allow the skin time to adjust and to monitor for any adverse reactions.

Additionally, formulations containing Biotinyl-Substance P must be scrutinized for potential comedogenic ingredients if users are prone to acne or have oily skin. While Biotinyl-Substance P itself is generally not associated with clogging pores, the accompanying formulation should be non-comedogenic to prevent potential breakouts.

As with any skincare ingredient, it is vital to use products containing Biotinyl-Substance P correctly and in accordance with the manufacturer’s instructions. Over-application or improper use can not only diminish the effectiveness of the product but may also increase the likelihood of experiencing side effects. Individuals who are pregnant, nursing, or have specific skin conditions should always consult with a dermatologist or healthcare provider before starting new skincare treatments to ensure safety and compatibility with existing health considerations.

In summary, while Biotinyl-Substance P is generally safe and beneficial for many users, individual reactions can vary, and cautious consideration should be given to personal skin condition, concurrent skincare products, and overall health before use. Regular consultation with skincare professionals can also aid in achieving optimal results and minimizing potential side effects.
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