Synonym |
Ile-Pro-Ile |
Species |
Human |
Protein Accession |
P30711 |
Purity |
≥98% |
Endotoxin Level |
<1.0 EU per 1 μg of the protein |
Biological Activity |
The ED50 is 0.2-1.5 μg/mL |
Expression System |
Escherichia coli |
Fusion Tag |
None |
Predicted Molecular Mass |
3149.4 Da |
Formulation |
Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA |
Reconstitution |
Reconstitute in water to a concentration of 0.1-1.0 mg/mL |
Storage & Stability |
Store at -20°C. For long term storage, store at -80°C. Stable for at least 1 year after receipt
when stored at -20°C |
FAQ
What is Diprotin A and how does it work?
Diprotin A is a tripeptide consisting of three amino
acids, Valine-Proline-Proline (VPP), that is gaining attention for its potential health benefits.
Derived from milk protein casein, Diprotin A is often discussed in the context of its ability to inhibit
the angiotensin-converting enzyme (ACE). The inhibition of ACE is significant because this enzyme plays
a crucial role in the body's regulation of blood pressure. By inhibiting ACE, Diprotin A may contribute
to lower blood pressure levels, which is particularly beneficial for those who are managing
hypertension. This mechanism is similar to the way some antihypertensive medications work, although
Diprotin A is a naturally occurring peptide.
The bioactive nature of Diprotin A makes it an area of
interest not just for cardiovascular health but also for metabolic conditions like diabetes. There is
ongoing research to determine how Diprotin A might influence insulin sensitivity and glucose metabolism.
Preliminary studies suggest that by improving insulin response, Diprotin A may help in managing blood
sugar levels. This could be particularly advantageous for individuals with type 2 diabetes or
prediabetes, who are looking for natural ways to regulate their blood sugar. Beyond these areas, there’s
also curiosity about Diprotin A’s potential impact on muscle recovery and immune system support. Its
presence in dairy products has made it a point of discussion among athletes and fitness enthusiasts who
consume high-protein diets. By integrating Diprotin A into the daily regimen, there’s a possibility of
reducing exercise-induced inflammation and muscle soreness, although more studies are required to
conclusively confirm these benefits. In summary, Diprotin A is a promising natural compound with
multifaceted benefits ranging from cardiovascular and metabolic health to potential positive effects on
muscle recovery and immunity.
What are the potential health benefits of Diprotin
A?
Diprotin A is garnering attention for its multifaceted health benefits, especially in the
realms of cardiovascular and metabolic health. One of its primary benefits lies in its ability to lower
blood pressure. By inhibiting the angiotensin-converting enzyme (ACE), Diprotin A assists in the
expansive process of vasodilation, thereby reducing overall blood pressure levels. This is particularly
beneficial for individuals who are managing hypertension. By promoting healthier blood pressure levels,
it helps reduce the risk of heart-related ailments and can be a part of a preventative strategy against
strokes and heart attacks. However, it should not replace conventional treatments but can certainly act
as a supplementary measure. In addition to cardiovascular benefits, Diprotin A may play a role in
regulating blood sugar levels. This is of particular interest to individuals dealing with type 2
diabetes or prediabetes. Its mechanism involves enhancing insulin sensitivity, allowing the body to more
effectively utilize glucose. This can lead to better management of blood sugar levels, adding another
layer of health protection for individuals with insulin resistance. Furthermore, Diprotin A may
contribute to improved digestion and reduced inflammation. The tripeptide has been studied for its
effects on gut health, particularly in balancing gut flora and potentially reducing symptoms of
inflammatory bowel disease. By fostering a healthy gut environment, it may consequently enhance nutrient
absorption and general well-being. Another intriguing area of Diprotin A’s benefits is in sports
nutrition and recovery. Athletes may experience decreased muscle soreness and improved recovery times
due to its anti-inflammatory properties. This could be beneficial, particularly in high-performance
sports where recovery speed is crucial. Beyond these, the potential antioxidant properties of Diprotin A
are being researched, adding another layer of possible health benefits, as antioxidants play key roles
in combatting oxidative stress and maintaining cellular health.
Are there any side effects
associated with Diprotin A?
While Diprotin A is generally considered safe for consumption, as
with any supplement or natural compound, it is crucial to be aware of potential side effects,
particularly when consumed in large quantities. Since Diprotin A is derived from dairy, individuals with
lactose intolerance or a milk allergy should exercise caution. Although the peptide itself might not
directly trigger lactose intolerance, the dairy-based origin of Diprotin A might still provoke symptoms
such as bloating, diarrhea, and stomach discomfort in sensitive individuals. For those with a severe
milk allergy, which is different from lactose intolerance, the concern is more pronounced, as milk
proteins can cause adverse reactions ranging from mild hives to more severe anaphylactic responses. As
such, individuals with known allergies should consult healthcare professionals before considering
Diprotin A as a supplement. Another potential consideration is the effect of Diprotin A on blood
pressure, particularly for individuals who may already be on antihypertensive medications. While one of
the benefits of Diprotin A is its potential to lower blood pressure through ACE inhibition, in some
cases, it may lead to blood pressure dropping too low if consumed with other medications designed to
lower blood pressure. This necessitates careful monitoring and adjustment by healthcare providers to
ensure that blood pressure remains within a safe range. Furthermore, it’s worth considering the purity
and source of Diprotin A supplements. Depending on the source, there might be variabilities in the
concentration and purity of the peptide, which could lead to unexpected side effects. Therefore, it is
advised to source Diprotin A from reputable, well-regulated suppliers to minimize the risk of
contaminants or inconsistencies in dosage. Lastly, while Diprotin A has potential benefits, ongoing
scientific studies continue to explore its long-term effects. As such, it is imperative for consumers to
remain informed of new research findings. Always consult with healthcare providers to ensure that any
new supplement, including Diprotin A, aligns with your personal health needs and conditions.
How
should Diprotin A be stored and taken?
Storing Diprotin A correctly is essential to maintain its
efficacy and shelf life. Like many supplements, the conditions under which Diprotin A is kept can
significantly impact its stability and effectiveness. Typically, Diprotin A should be stored in a cool,
dry place away from direct sunlight. Excessive heat or moisture can degrade the peptide’s structure,
diminishing its benefits over time. A pantry or a cupboard that maintains a consistent temperature is
usually ideal. It is also important to ensure that the container is tightly sealed after each use to
prevent exposure to air and moisture. Some individuals might refrigerate Diprotin A to help prolong its
shelf life, especially in warmer climates, although this is not necessarily required. However, if you do
choose to refrigerate, ensure that the supplement is tightly sealed and kept away from strong-smelling
foods, as supplements might sometimes absorb odors. When it comes to the actual consumption of Diprotin
A, following the manufacturer's recommendations is crucial. Since Diprotin A can be concentrated in
varied dosages depending on the product and its intended use, it is advisable to adhere to the suggested
serving size detailed on the packaging or provided by a healthcare provider. Typically, Diprotin A may
be consumed once or twice a day, possibly with meals to aid digestion and absorption. Taking it during
or just after a meal can also decrease the likelihood of stomach upset, which can occasionally occur
with peptide supplements. It’s also worth considering the timing of taking Diprotin A, particularly if
it is used to manage health conditions like hypertension. Some individuals may find it beneficial to
take the supplement at a specific time each day to help regulate blood pressure consistently. This might
be in the morning or before bedtime, according to what fits best with their daily routine and aligns
with advice from healthcare providers. Lastly, consistency is key. For perceived benefits, Diprotin A
should be incorporated as a regular part of your health and wellness routine, and adjustments to your
intake should be made only based on specific health needs and advice from a medical or health
professional.
Can Diprotin A be taken with other supplements or medications?
The
interaction of Diprotin A with other supplements or medications is an important consideration, given
that it acts as an ACE inhibitor. First and foremost, if Diprotin A is being considered alongside
antihypertensive medications, one must be cautious. Both ACE inhibitor medications and Diprotin A lower
blood pressure, so there is potential for an additive effect that could lead to hypotension, or
excessively low blood pressure. Monitoring by a healthcare provider is essential in this situation to
ensure blood pressure levels remain within a healthy range, and adjustments to medication dosages might
be necessary. When it comes to other dietary supplements, combining Diprotin A with protein supplements
is generally deemed safe, as both address different aspects of health. However, pay attention to the
protein source; since Diprotin A comes from dairy, combining it with other dairy-based supplements or
foods could enhance its effects. Alternatively, if someone is mixing supplements for metabolic health,
such as those involving chromium or alpha-lipoic acid which aid in blood sugar metabolism, they might
find an enhanced effect with Diprotin A due to its potential influence on insulin sensitivity. Having
said that, it is always advisable to introduce supplements gradually and observe how your body responds
to any changes. Additionally, herbal supplements such as garlic, hawthorn, or ginseng, known for
cardiovascular benefits, should be taken with caution. These may also lower blood pressure or improve
circulation and, when taken with Diprotin A, could lead to compounded effects. The specific interactions
could vary based on individual health conditions and the unique pharmacodynamics of each herb, so
professional guidance is highly recommended in these cases. Lastly, consider any current health
conditions or metabolic concerns you might have. Sometimes, the addition of multiple supplements can
lead to unforeseen interactions not just between the supplements themselves, but between the supplements
and your personal health variables. Therefore, after establishing a consistent diet and supplement plan,
consider periodic reviews with a nutritionist or healthcare provider. This will ensure that the
combination of supplements and medications continues to be safe and effective within the context of your
broader health picture.