Synonym |
H-NRNFLRF-NH2 |
Species |
Human |
Protein Accession |
NA |
Purity |
Greater than 95% as determined by HPLC |
Endotoxin Level |
Less than 1 EU/ug |
Biological Activity |
NA |
Expression System |
Chemical synthesis |
Fusion Tag |
NA |
Predicted Molecular Mass |
957.08 Da |
Formulation |
Lyophilized from a 0.2 μm filtered solution of Acetonitrile and TFA |
Reconstitution |
It is recommended to reconstitute the lyophilized H-NRNFLRF-NH2 in sterile 18MΩ-cm H2O not less
than 100μg/ml, which can then be further diluted to other aqueous solutions. |
Storage & Stability |
Lyophilized H-NRNFLRF-NH2 although stable at room temperature for 3 weeks, should be stored
desiccated below -18°C. Upon reconstitution H-NRNFLRF-NH2 should be stored at 4°C between 2-7
days and for future use below -18°C. For long term storage it is recommended to add a carrier
protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
FAQ
What is the nature and primary function of the compound H-NRNFLRF-NH2?
H-NRNFLRF-NH2 is a peptide
compound that falls under a specific class of biochemical molecules known for their diverse
physiological roles in biological organisms. Peptides like H-NRNFLRF-NH2 are short chains of amino acids
linked by peptide bonds, serving as fundamental components in numerous cellular processes. The primary
structure, sequence, and length of peptides determine their function and interaction in biological
systems. In the case of H-NRNFLRF-NH2, it likely functions as a signaling or regulatory peptide, which
may have roles in modulating neurological, immune, or metabolic pathways. Such compounds are of great
interest in biomedical research due to their potential therapeutic benefits. The specific sequence of
amino acids in H-NRNFLRF-NH2 denotes its unique properties and contributes to its binding affinity,
specificity, and biological activity. Common functions of peptides like this can include acting as
neurotransmitters, hormones, or growth factors, and they may be involved in vital processes such as cell
signaling, immune response modulation, and enzymatic activity regulation. The study of specific peptides
involves examining their synthesis pathways in organisms, the receptors they bind to, and the downstream
effects they elicit. These peptides can offer a high degree of specificity in interaction with their
targets, making them useful in precise therapeutic interventions.
How might H-NRNFLRF-NH2 play a
role in scientific research?
In scientific research, H-NRNFLRF-NH2 represents a promising avenue for
studying complex biological systems due to its potential roles as a signaling molecule. Peptides similar
to H-NRNFLRF-NH2 are often utilized in experimental contexts to elucidate cellular pathways, understand
disease mechanisms, and develop novel therapeutic strategies. Their specific interactions with cell
surface receptors or enzymes make them ideal candidates for dissecting signal transduction pathways. For
instance, if H-NRNFLRF-NH2 is involved in neurological signaling, it could be used to study synaptic
transmission or neuroplasticity, contributing to a better understanding of disorders such as Alzheimer's
or Parkinson's disease. Furthermore, peptides can be used in pharmacological research as models for drug
design and development. Peptide-based therapies are increasingly becoming a focus in treating various
conditions due to their high specificity and low toxicity profiles. By manipulating or modifying
H-NRNFLRF-NH2, researchers could develop new drugs that mimic its action or enhance its desired effects.
In addition, such peptides are valuable in diagnostic applications, where they can be used as biomarkers
for specific diseases or conditions, aiding in early detection and management. The utility of
H-NRNFLRF-NH2 in these contexts requires rigorous scientific investigation, including structure-activity
analysis, determination of bioavailability, and evaluation of therapeutic potential.
What
distinguishes H-NRNFLRF-NH2 in terms of its chemical structure and stability?
The chemical structure
of H-NRNFLRF-NH2 distinguishes it from other peptides and contributes to its unique properties. At the
molecular level, peptides are characterized by specific sequences of amino acids, and in the case of
H-NRNFLRF-NH2, this sequence is known for imparting distinct physiological activities. Particularly, the
structure comprises an N-terminal protection with an 'H' group and a C-terminal amide, denoted by NH2,
contributing to its stability and resistance against enzymatic degradation. Such modifications are
critical in enhancing the peptide's half-life, bioavailability, and overall functional utility in
biological systems. The presence of particular amino acids in the sequence, such as those with aromatic
or basic side chains, further influences its binding affinity and specific interactions with biological
receptors. Stability in peptides like H-NRNFLRF-NH2 is not solely dependent on structural modifications
but also on their secondary and tertiary folding. The manner in which the peptide folds can affect its
solubility and resistance to thermal and enzymatic breakdown, crucial for maintaining its bioactivity.
Peptides often require a precise conformation to achieve desired biological effects, and any deviation
can significantly alter their functionality. Research into the chemical stability of H-NRNFLRF-NH2
entails examining conditions such as pH, temperature, and solvent interactions that might impact its
efficacy. Understanding these factors helps in formulating the peptide for research and potential
clinical applications, ensuring it remains active and potent within desired environments.
What
therapeutic implications can be associated with H-NRNFLRF-NH2?
The therapeutic implications of
H-NRNFLRF-NH2 are promising, given its potential role as a biologically active peptide. Peptides like
H-NRNFLRF-NH2, characterized by their specific amino acid sequences and biological activity, can serve
as precursors or basis for the development of new drugs targeting a wide range of diseases. Depending on
its mechanism of action, H-NRNFLRF-NH2 could serve as a candidate for therapeutic interventions in areas
such as cardiovascular health, neurological disorders, and metabolic syndromes. For instance, if it
interacts with neural receptors, it might be harnessed to treat neurodegenerative diseases or cognitive
disorders by modulating neurotransmitter release or receptor signaling pathways. Additionally, its
application in cardiovascular health could involve regulating blood pressure or heart functions by
interacting with related peptide receptors. The specificity and efficacy of peptides like H-NRNFLRF-NH2
originate from their ability to mimic or interfere with natural biological processes selectively. Unlike
traditional small-molecule drugs, peptides have a reduced risk of off-target effects, potentially
leading to safer treatment options. However, to capitalize on the therapeutic potential of
H-NRNFLRF-NH2, challenges such as delivery mechanisms, stability, and bioavailability need to be
addressed. Modern pharmaceutical advancements, including nanoparticle and liposome technologies, offer
innovative solutions to these challenges by improving the delivery and absorption of peptide-based
drugs. Ongoing research is essential to determine the clinical feasibility of H-NRNFLRF-NH2, involving
rigorous preclinical and clinical testing to assess its safety, efficacy, and potential side
effects.
Can H-NRNFLRF-NH2 influence biomedical advancements or innovation?
H-NRNFLRF-NH2 can
significantly influence biomedical advancements by serving as a tool in research and development
processes aimed at understanding complex biological mechanisms and developing targeted therapies.
Peptides like this one are instrumental in pushing the boundaries of biomedical research due to their
versatility and specificity. In the laboratory setting, they can be synthesized and modified to study
their precise roles in various biological processes, thereby contributing to the broader understanding
of health and disease. By providing insights into cellular signaling pathways, immune responses, and
hormonal regulation, H-NRNFLRF-NH2 can shape the development of new therapeutic strategies.
Additionally, the study of such peptides contributes to the innovation of novel methodologies and
technologies in biomedical science. Techniques such as peptide synthesis, peptide libraries, and
high-throughput screening are direct outcomes of peptide research and have broad applications in drug
discovery and molecular biology. These innovations are critical for identifying new drug candidates,
understanding target-ligand interactions, and developing personalized medicine approaches. Moreover, the
knowledge gained from studying H-NRNFLRF-NH2 could pave the way for bioengineered peptides that mimic or
enhance human physiological functions, potentially providing solutions for complex diseases that current
treatments cannot adequately address. In essence, the exploration of H-NRNFLRF-NH2 offers an avenue for
discovering groundbreaking applications in healthcare, ranging from new diagnostic tools to
sophisticated therapeutic agents, ultimately contributing to the advancement of medical knowledge and
patient care solutions.