Synonym |
H-p-Cl-Phe-D-Cys-β-(3-pyridyl)Ala-D-Trp-N-M |
Species |
Human |
Protein Accession |
Not available |
Purity |
Not specified |
Endotoxin Level |
< 1 EU/μg |
Biological Activity |
Not determined |
Expression System |
E. coli |
Fusion Tag |
None |
Predicted Molecular Mass |
Not available |
Formulation |
Lyophilized |
Reconstitution |
Reconstitute in water to a concentration of 0.1-1.0 mg/ml |
Storage & Stability |
Store at -20°C. For long term storage, store at -70°C or below. Stable for 12 months after
receipt. |
FAQ
What is H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-M used for, and how does it
function?
H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-M primarily functions as a scientific
research chemical. This compound is frequently utilized in biochemical studies and experiments due to
its distinctive structure and properties. Researchers are particularly interested in its interaction
with various biological receptors, which could potentially elucidate new pathways in pharmacology. The
compound’s configuration allows it to bind selectively to specific cellular targets, making it an
excellent tool for analyzing receptor activities and ligand interactions at the molecular level. These
characteristics make it invaluable in investigating the structural and functional aspects of
receptor-ligand interactions.
In studying this compound, scientists might gain insights into its
efficacy and potential as a therapeutic agent. By understanding how
H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-M interacts with receptors, researchers can develop
models to predict its behavior in living organisms. This understanding can lead to the development of
similar compounds that could work as treatments for various diseases, particularly those affecting the
neurological or immune systems. The compound's ability to interact within these systems makes it an
important candidate for research aimed at drug discovery and development.
Additionally, this
compound's study can assist in tracing biological signaling pathways. Scientists can employ
H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-M to identify potential therapeutic targets within these
pathways. By analyzing how the compound affects these pathways, research can propose new strategies for
intervention in cases of dysregulation, which is often a characteristic in diseases like cancer or
autoimmune disorders. Therefore, the intrinsic scientific value of
H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-M lies in its ability to help researchers delve into
pivotal questions about biological function and interaction, which can lead to substantial advancements
in medical science and pharmacology.
How should H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-M
be handled and stored in a laboratory setting to ensure safety and stability?
Handling and
storing H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-M requires adherence to specific safety
guidelines to maintain its stability and to ensure safety in the laboratory. Firstly, it's crucial to
understand that this compound should always be handled in a controlled environment, typically a
laboratory equipped to handle biochemical substances. Personal protective equipment (PPE), such as lab
coats, gloves, and safety goggles, should be worn at all times to prevent any accidental exposure. The
compound should be handled under a fume hood to prevent inhalation of any potentially hazardous
fumes.
The storage of H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-M also demands careful
attention to detail. It should be kept in a dry, cool environment, typically at temperatures recommended
by accompanying material safety data sheets or other relevant documentation. The vials or storage
containers should be firmly sealed to prevent atmospheric moisture from affecting the compound, as
exposure to moisture can lead to degradation or other unwanted reactions. Labels on the containers
should be clear and precise, including the substance name, concentration, and any hazard warnings, to
prevent mishandling by laboratory personnel.
In addition, it is important that the storage area
for this compound is secure yet accessible only to trained personnel. This ensures that the compound is
not only protected against unauthorized access but also is handled by individuals who understand the
necessary safety protocols. Laboratories should also be equipped with spill kits and first aid equipment
tailored for chemical exposure to swiftly address any accidents that might occur. Furthermore, safety
procedures should be periodically reviewed and updated to ensure compliance with the latest safety
standards and regulations. This comprehensive approach to handling and storing
H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-M not only upholds safety but also aids in maintaining
the integrity of the compound for future research.
What are the potential risks associated with
the research use of H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-M, and how can these be
mitigated?
The research use of H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-M, like many
research chemicals, comes with potential risks which can be effectively mitigated through rigorous
safety protocols. One of the primary risks involves the compound’s toxicological profile, which may not
be entirely understood. Handling and exposure might result in unexpected allergic reactions or toxic
effects if proper precautions are not taken. The use of personal protective equipment (PPE)—such as
gloves, lab coats, and eye protection—can significantly reduce the risk of direct exposure to the skin
or eyes, which is a main concern with chemical handling.
Beyond physical exposure, there is also
the risk related to inhalation or accidental ingestion. Laboratories should have proper ventilation
systems, such as fume hoods, that help prevent airborne exposure to the compound. Furthermore, all
individuals working in the lab should be trained on how to handle chemicals properly, including
procedures for what to do if accidental ingestion occurs. Having a seated safety officer or a trained
personnel member responsible for overseeing the laboratory’s safety procedures can be an effective
strategy for ensuring that safety protocols are routinely followed.
To mitigate these risks, it’s
also important to understand the stability and reactivity profile of
H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-M. Regularly consulting safety data sheets and other
available resources can provide detailed information on safe handling practices and known
incompatibilities with other chemicals. Regular safety drills and continuous education on new safety
protocols can help maintain a high level of preparedness among research staff.
In addition to
personal safety measures, researchers should also maintain comprehensive documentation of all
experimental procedures and observational data. Such documentation serves as a valuable resource for
assessing the safety and efficacy of the compound, providing insight into its potential risks during
usage. By integrating these approaches, laboratories can effectively establish a culture of safety that
not only mitigates risks associated with using H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-M but also
facilitates high-quality, safe research outcomes.
What makes
H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-M of interest in pharmaceutical
research?
H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-M represents a significant subject of
interest in pharmaceutical research due to its complex biochemical attributes and its potential
implications for drug discovery and therapeutic applications. The structural uniqueness of this compound
allows it to interact with specific biological targets, which researchers are interested in studying to
further understand various biochemical pathways. Such interactions can shed light on certain
physiological processes and pathological conditions, opening up new avenues for pharmaceutical
exploration.
One of the primary facets of interest is the compound's potential to act as a
modulator of receptor activity. Many diseases, particularly those affecting the central nervous system
or immune responses, are due to dysfunctional receptor-ligand interactions. By elucidating these
interactions, the compound serves as a model that can potentially lead to the development of new drugs
aimed at restoring normal receptor function. Additionally, researchers are keen to explore the
compound’s possible role as an inhibitor or activator within these systems, which would be valuable in
designing therapies that require precise modulation of cellular responses.
Furthermore,
H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-M can be used in high-throughput screening assays to
identify binding sites for pharmaceutical agents. In these assays, the compound can help identify
specific interactions which could be exploited in the development of drugs that need to precisely target
certain proteins or receptors. This selectivity is crucial in therapeutic design to ensure that drugs
act effectively on diseased cells or tissues with minimal side effects.
Another striking point of
interest is the potential for the compound to provide insights into protein folding and
structure-function relationships. Misfolded proteins contribute to a range of diseases, including
neurodegenerative disorders. Studies involving H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-M might
provide valuable data on how certain chemical alterations influence protein configurations, thus
contributing to the understanding of conditions like Alzheimer's or Parkinson's disease.
In
conclusion, H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-M is of considerable interest in
pharmaceutical research due not just to its potential as a standalone therapeutic agent, but also for
its role in building foundational knowledge that can advance drug discovery and development. Its unique
interactions at the molecular level could offer unprecedented insights into treating diseases with
complex biochemical underpinnings.
Can you discuss the potential contributions of
H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-M to understanding disease pathways?
The compound
H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-M holds significant promise in advancing our
understanding of disease pathways due to its potential as a probe capable of elucidating complex
biochemical mechanisms. A cornerstone of modern biomedical research is identifying and characterizing
the precise molecular and cellular processes underlying disease states, which is where this compound
comes into play. By studying how H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-M interacts with cell
receptors or enzymes, researchers can gain insights into the initiation and progression of diseases,
particularly those with complex pathophysiologies such as cancer, neurodegenerative diseases, and
autoimmune disorders.
For instance, the compound's potential ability to modulate receptor
activities can reveal the intricacies of signal transduction pathways that are often deregulated in
cancer. By understanding which pathways H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-M influences,
researchers can map out how certain oncogenes trigger abnormal cell proliferation, migration, or
survival. This detailed knowledge might uncover vulnerabilities in cancer cells that can be targeted
therapeutically, thus providing a roadmap for the development of precise cancer
treatments.
Moreover, the neuropharmacological interest in
H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-M also extends to neurodegenerative conditions like
Alzheimer's and Parkinson's disease. These disorders are characterized largely by misfolded proteins and
disrupted neurotransmitter signaling. Investigations into how this compound affects synaptic activity or
protein structure could illuminate the biochemical missteps leading to neurodegeneration, enabling the
design of interventions aimed at halting or reversing disease
progression.
H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-M can also serve as a molecular tool
to dissect autoimmune responses. Autoimmune diseases are marked by the body's immune system identifying
its own cells as foreign, leading to chronic inflammation and tissue damage. By using this compound to
study immune receptor signaling, scientists may identify specific pathways that become hyperactive in
these diseases, thus providing targets for immunomodulatory therapies.
Overall, the contribution
of H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-M to understanding disease pathways is potentially
profound, offering insights that can facilitate the discovery of novel therapeutics. Through detailed
exploration of its interactions within biological systems, this compound promises to deepen our
comprehension of how diseases develop at the molecular level, paving the way for innovative and
effective medical interventions.