| Synonym | 
                    Hydrin 2% (Arg8,Gly10)-Vasotocin | 
                
                
                    | Species | 
                    Human | 
                
                
                    | Protein Accession | 
                    P01185 | 
                
                
                    | Purity | 
                    ≥ 95% | 
                
                
                    | Endotoxin Level | 
                    
                        < 1 EU/μg | 
                
                
                    | Biological Activity | 
                    Not specified | 
                
                
                    | Expression System | 
                    E. coli | 
                
                
                    | Fusion Tag | 
                    No tag | 
                
                
                    | Predicted Molecular Mass | 
                    1084.22 Da | 
                
                
                    | Formulation | 
                    Lyophilized from a 0.2 μm filtered solution of 20% acetonitrile in 0.1% trifluoroacetic acid
                     | 
                
                
                    | Reconstitution | 
                    It is recommended to reconstitute the lyophilized product with sterile water at a concentration
                        of 0.1 mg/ml, which can then be further diluted to other aqueous solutions | 
                
                
                    | Storage & Stability | 
                    Store lyophilized protein at -20°C. Aliquot reconstituted protein and store at -80°C. Avoid
                        repeated freeze-thaw cycles. | 
                
            
            FAQ
            
                What is Hydrin 2, (Arg8,Gly10)-Vasotocin, and what are its primary applications?
Hydrin 2, also
                known as (Arg8,Gly10)-Vasotocin, is a synthetic analog of the naturally occurring peptide known as
                vasotocin. Vasotocin itself is a nonapeptide that serves important roles in various animal species,
                especially in birds, reptiles, and amphibians. It is often considered homologous to both arginine
                vasopressin and oxytocin found in mammals. The significance of Hydrin 2 lies in its ability to replicate
                some of the essential biological activities of vasotocin, which makes it a vital tool in scientific
                research exploring neuroendocrinology, behavior, and evolutionary biology. One of its primary
                applications is in the study of social behavior and stress responses across different
                species.
Hydrin 2 is invaluable in research due to its ability to bind to vasotocin receptors,
                which are ancestral to the vasopressin and oxytocin receptors found in mammals. These receptors are
                known to influence an array of physiological processes including water balance, blood pressure
                regulation, and reproduction. In the context of behavioral studies, Hydrin 2 is employed to investigate
                its effects on social bonding, mating behaviors, and aggression. By observing these interactions,
                researchers can gain insights into the evolutionary mechanisms that guide social relations and
                environmental adaptations.
Furthermore, Hydrin 2 is also significant in agricultural studies.
                Understanding its role in avian species, for example, can aid in developing strategies for optimizing
                reproduction or managing stress in poultry, thereby contributing to more efficient and humane farming
                practices. It lends itself to conservation efforts as well, as it helps in understanding how various
                species might adapt to changing environmental stresses or social structures within their populations.
                Additionally, insights drawn from such studies may also be applicable to understanding endocrine systems
                in humans, potentially aiding in the development of treatments for disorders related to water retention,
                blood pressure, and social behavioral issues.
Overall, the application of Hydrin 2 reaches beyond
                basic scientific inquiry; it can influence ecological management and animal husbandry while potentially
                offering translational insights applicable to human health. Its versatility as a research compound
                underscores its importance in bridging gaps between comparative physiology and applied sciences.
                Researchers harnessing Hydrin 2 are thus poised to glean transformative insights that span diverse
                fields, strengthening our comprehension of biological frameworks and evolutionary links across
                species.
How does Hydrin 2, (Arg8,Gly10)-Vasotocin, compare to traditional vasopressin and
                oxytocin in terms of functionality and research importance?
Hydrin 2, (Arg8,Gly10)-Vasotocin,
                shares significant structural and functional similarities with the well-known peptides vasopressin and
                oxytocin. However, it holds distinct differences in terms of evolutionary context and specific receptor
                interactions which make it particularly valuable for research in non-mammalian species. While
                vasopressin and oxytocin are predominant in mammals and widely studied for their roles in regulating
                water retention, blood pressure, and social behaviors, Hydrin 2 offers a broader panorama into the
                ancestral pathways of these peptides. 
Functionally, vasotocin acts akin to both vasopressin and
                oxytocin, being involved in osmoregulation and social behaviors. However, its functionality is broader,
                as it serves as a prototype to understand the evolutionary transition of these hormones. Despite these
                similarities, it holds distinctive roles across various species that are not fully replicated by the
                mammalian hormones. Vasotocin tends to influence behaviors such as territoriality, mating, and nesting
                particularly within birds and amphibians. Therefore, studying Hydrin 2 can provide a unique window into
                understanding how certain social behaviors evolved as well as how they are maintained or modified in
                animal populations. 
From an evolutionary biology perspective, Hydrin 2 highlights the molecular
                divergence and adaptation occurring over millions of years that led to the specialized roles of
                vasopressin and oxytocin in mammals. This makes it an indispensable tool not only for comparative
                studies across different phylogenetic lineages but also for reconstructing the functional evolution of
                neuropeptides. Additionally, Hydrin 2's ability to activate both oxytocin and vasopressin receptors
                underlines its versatility and why it's a compound of interest for comprehensive receptor pathway
                studies.
While vasopressin and oxytocin are extensively linked to clinical applications because
                of the vast array of physiological processes they influence in humans, Hydrin 2 is mostly pivotal in the
                domain of basic research. However, the lessons learned from Hydrin 2 can potentially inform medical
                research as they unravel foundational aspects of receptor functionality and evolutionary conserved
                mechanisms that might mirror pathophysiological conditions in humans. Ultimately, it holds significant
                promise in evolutionary biology, endocrinology, and behavioral science, aiding the understanding of
                complex interactions within natural habitats that might otherwise go unnoticed if relying solely on the
                mammalian models.
What scientific investigations are advanced by the use of Hydrin 2,
                (Arg8,Gly10)-Vasotocin?
Hydrin 2, (Arg8,Gly10)-Vasotocin, plays a pivotal role in various
                scientific investigations, particularly in the fields of endocrinology, neurobiology, and evolutionary
                biology. The unique properties of Hydrin 2 enable researchers to explore the effects of neuropeptides on
                animal behavior and physiology in ways that traditional studies using vasopressin and oxytocin do not
                fully capture. One significant area of study is the investigation of social behaviors in non-mammalian
                species, such as birds, amphibians, and reptiles. These studies aim to better understand the
                physiological underpinnings of behaviors like mating rituals, parental care, and territorial aggression.
                Hydrin 2 serves as a crucial variable in experiments designed to discern how hormonal pathways influence
                such complex behavioral patterns. 
In addition to behavioral studies, Hydrin 2 is extensively
                used to understand mechanisms of osmoregulation and stress response across different species. This
                nonapeptide is known to be intricately involved in regulating the balance of water and salts within an
                organism, particularly within avian species. Through detailed analyses, scientists seek to delineate how
                Hydrin 2 helps animals adapt to varying environmental conditions, which could have implications for
                understanding climate adaptability among wildlife. Furthermore, research using Hydrin 2 delves into how
                neuropeptide systems have evolved, bridging the gap between primitive hormonal systems and the more
                advanced neuroendocrine systems found in higher vertebrates. 
The insights gained from these
                studies not only elucidate the adaptive strategies used by different species but also provide
                comparative models that may mimic certain human biological processes, offering indirect benefits to
                medical science. Hydrin 2's influence extends to agricultural science as well, where it aids in
                examining the effects of stress and reproduction in livestock, potentially influencing practices aimed
                at improving animal welfare and productivity. Conservation biology also benefits from investigations
                with Hydrin 2, as it helps identify how natural or anthropogenic stressors might affect the physiology
                and behaviors of endangered species, which is crucial for developing effective management strategies.
                All these facets underline the multifaceted applications of Hydrin 2 in scientific inquiry,
                demonstrating how a single peptide can enhance our understanding of biology and improve applied
                scientific methodologies across a range of disciplines.
What are the potential benefits of
                studying Hydrin 2, (Arg8,Gly10)-Vasotocin, in birds?
Exploring the effects of Hydrin 2,
                (Arg8,Gly10)-Vasotocin, in birds opens the door to a multitude of insights into avian biology,
                particularly in understanding how neuroendocrine mechanisms regulate behavioral and physiological
                processes. One of the key benefits of studying Hydrin 2 in birds lies in its role in deciphering complex
                social behaviors. Bird species exhibit a diverse array of social structures and mating systems, from
                monogamy to polygyny, making them ideal models for examining how peptides like Hydrin 2 influence social
                bonding, hierarchical interactions, and reproductive strategies. By manipulating levels of Hydrin 2 and
                observing resultant behavioral changes, researchers can infer how hormonal pathways dictate mating
                rituals, territorial defense, and parental care behaviors. These insights can subsequently be correlated
                with evolutionary pressures that have shaped these behaviors, providing a deeper understanding of the
                adaptive significance of social structures in avian life.
Aside from its behavioral implications,
                Hydrin 2 also offers critical benefits for physiological studies. As a regulator of osmoregulation, it
                plays a fundamental role in adaptation to different environmental conditions, especially in bird species
                that inhabit arid or saline environments. By studying Hydrin 2 in these species, scientists gain a
                clearer understanding of the physiological adjustments that allow birds to thrive in challenging
                habitats. Such knowledge could be invaluable in predicting how birds might cope with the ongoing impacts
                of climate change, which presents new challenges in terms of resource availability and habitat
                conditions.
Furthermore, examining the effect of Hydrin 2 on avian physiology can have direct
                applications in conservation science. Through understanding how it affects stress responses, researchers
                can better assess the impact of habitat disruption and human-induced environmental changes on bird
                populations. Effective conservation strategies can then be devised, targeting enhancements in habitat
                management and amelioration of stressors that impact breeding success and survival rates.
In
                aviculture and poultry science, research into Hydrin 2 might lead to enhancements in breeding programs
                by optimizing conditions conducive to desired behaviors and stress management. This has implications not
                only for production efficiency but also for animal welfare standards. Overall, the benefits of studying
                Hydrin 2 in birds are extensive, providing vital contributions to behavioral ecology, physiology,
                conservation, and agriculture, thereby facilitating a holistic understanding of avian species in their
                natural and managed environments.
How does the study of Hydrin 2, (Arg8,Gly10)-Vasotocin,
                contribute to our understanding of evolutionary biology?
The study of Hydrin 2,
                (Arg8,Gly10)-Vasotocin, is instrumental in unraveling the complexities of evolutionary biology,
                particularly concerning the evolution of endocrine and neuroendocrine systems across vertebrates.
                Vasotocin is often considered an ancestral peptide from which the mammalian peptides vasopressin and
                oxytocin evolved. By studying Hydrin 2, researchers can glean insights into the evolutionary journey of
                neuropeptide systems and understand how these molecules have adapted to fulfill varied and complex
                biological roles in different species. 
In exploring Hydrin 2, scientists can trace the
                phylogenetic differences in receptor binding affinities and responses to the peptide across a diverse
                array of species. These studies contribute to a more comprehensive understanding of the molecular
                evolution of receptor-ligand interactions, highlighting the adaptive modifications that have been shaped
                by evolutionary pressures. The results enhance our grasp of how ancient peptide systems have diversified
                in structure and function, giving rise to the sophisticated hormonal networks observed in modern
                vertebrates.
Through comparative studies using Hydrin 2, researchers are also able to understand
                the evolutionary roots of social behaviors, providing a framework for evaluating how such behaviors
                might have conferred selective advantages. By identifying the conserved and divergent elements of
                vasotocin-mediated behaviors, scientists can hypothesize how certain social traits evolved in response
                to environmental challenges. This is invaluable for reconstructing the behavioral evolution of
                lineage-specific traits that are crucial for survival and reproduction.
Moreover, Hydrin 2 serves
                as a model for studying the evolution of osmoregulatory and stress response mechanisms. Given its role
                in regulating water balance and adaptation to environmental stresses, research on Hydrin 2 helps explain
                how different species evolved strategies for maintaining homeostasis under varying ecological
                conditions. This aids in understanding the evolutionary pathways that have led to the phenotypic
                diversity observed in today's vertebrate populations, underpinning the adaptability and resilience of
                life forms in dynamic ecosystems.
Ultimately, Hydrin 2 not only contributes to the field of
                evolutionary biology by providing insights into the fundamental processes that drive biological
                diversity and organismal adaptation but also reinforces the interconnected nature of life, offering
                perspectives that improve our overall comprehension of biological evolution and its impacts on current
                biodiversity.