Synonym |
LYK |
Species |
Human |
Protein Accession |
P01234 |
Purity |
≥ 95% |
Endotoxin Level |
< 1.0 EU per 1 μg of the protein |
Biological Activity |
The ED50 is 2-10 ng/mL |
Expression System |
E. coli |
Fusion Tag |
None |
Predicted Molecular Mass |
3.5 kDa |
Formulation |
Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH 8.0 |
Reconstitution |
Centrifuge briefly and reconstitute in sterile distilled water |
Storage & Stability |
Store at -20°C upon receipt, stable for up to 3 months at -20°C |
FAQ
What is Lys-Tyr-Lys and what are its key benefits?
Lys-Tyr-Lys is a tri-peptide composed of three
amino acids: lysine (Lys), tyrosine (Tyr), and another lysine (Lys). This unique combination offers a
variety of benefits, particularly in the realm of skincare and health. Each of these amino acids plays a
critical role in biological functions, which translates into potential advantages when used in
formulations designed for topical application or other health-promoting products. Lysine is an essential
amino acid, meaning our bodies cannot synthesize it and it must be obtained from dietary sources. It is
crucial for protein synthesis, collagen formation, and the absorption of calcium. This makes lysine an
invaluable component in skincare, as collagen is a vital protein that provides structure, elasticity,
and firmness to the skin. The presence of lysine in Lys-Tyr-Lys can therefore contribute to improved
skin texture and the reduction of wrinkles. Tyrosine, on the other hand, is a non-essential amino acid
that serves as a precursor to several vital neurotransmitters, including dopamine, norepinephrine, and
epinephrine. In skincare, tyrosine is known for its role in the production of melanin, the pigment
responsible for skin color. It can also help in stress recovery by supporting neurotransmitter
production, potentially enhancing the overall mood and reducing the signs of aging that are exacerbated
by stress. The inclusion of tyrosine in Lys-Tyr-Lys brings an added layer of protection and revitalizing
effects to the skin. With lysine once again completing the tri-peptide, this strategic repetition
amplifies the benefits of enhanced collagen synthesis and skin immunity. Overall, Lys-Tyr-Lys serves as
a powerhouse in maintaining skin health, promoting a youthful complexion, and potentially offering
neurological benefits through the tyrosine component. It is, therefore, a sought-after ingredient in
advanced skincare products and health supplements that aim to deliver both aesthetic and physiological
benefits.
Can Lys-Tyr-Lys be used for all skin types?
Lys-Tyr-Lys has gained recognition
for its versatility and efficacy, making it suitable for use across a wide range of skin types. The
tri-peptide format allows it to address various skin concerns while minimizing the risk of irritation,
which is a common concern when using potent skincare active ingredients. Individuals with sensitive skin
often experience adverse reactions to new products, so the gentle nature of Lys-Tyr-Lys is a notable
advantage. The presence of lysine helps reinforce the skin's natural barrier, improving its resilience
against environmental stressors and maintaining hydration. This makes it particularly beneficial for
those with sensitive or reactive skin who need extra protection and soothing effects. Oily and
acne-prone skin types can also benefit from Lys-Tyr-Lys. The anti-inflammatory properties of lysine help
reduce redness and swelling associated with acne, while tyrosine aids in cellular repair and turnover.
The combination can help balance oil production and support a clearer complexion. For dry skin types,
Lys-Tyr-Lys presents a hydrating and reparative quality. The enhancement of collagen synthesis through
lysine contributes to improved moisture retention and structural integrity of the skin, reducing the
appearance of fine lines and enhancing overall skin texture. Normal and combination skin types enjoy the
comprehensive benefits offered by Lys-Tyr-Lys without the need for additional adjustments. These skin
types can appreciate the tri-peptide's ability to maintain balance, support elasticity, and provide a
radiant, even complexion. It’s important to note that while Lys-Tyr-Lys is generally well-tolerated,
individual sensitivity can vary. As with introducing any new skincare product, it is advisable to
perform a patch test to ascertain compatibility with one's skin. By starting with a small application
and gradually increasing usage, users can effectively integrate Lys-Tyr-Lys into their routine
regardless of their skin type, reaping the diverse array of benefits it offers.
How does
Lys-Tyr-Lys compare to other peptides used in skincare?
In the realm of skincare, peptides have
emerged as crucial components for targeting a multitude of concerns ranging from aging to hydration to
skin repair. Lys-Tyr-Lys stands out among these peptides due to its unique composition and the combined
effects of its constituent amino acids. Unlike single peptides with limited functionality, tri-peptides
like Lys-Tyr-Lys bring together multiple aspects of skin health into one cohesive compound. Traditional
skincare peptides often focus on a singular function such as boosting collagen (e.g., palmitoyl
pentapeptide-4) or minimizing expression lines (e.g., acetyl hexapeptide-8, known as Argireline). While
effective, these peptides usually target specific concerns. Lys-Tyr-Lys, however, operates on an
integrated approach. By incorporating lysine, it directly contributes to collagen production and skin
resilience. The recurring presence of lysine reinforces this function, leading to cumulative benefits
over time, assisting in long-term skin strengthening and rejuvenation. Additionally, the inclusion of
tyrosine in Lys-Tyr-Lys introduces melanin synthesis support, offering a brighter and more even skin
tone, a feature not commonly addressed by typical anti-aging peptides. The natural structure and
interaction of the amino acids in Lys-Tyr-Lys mimic the skin's unique peptide components, potentially
easing cellular assimilation and effectiveness. This molecular mimicry could provide an added advantage
over synthetic or disparate peptide chains that require greater cellular adaptation. The systemic
effects of Lys-Tyr-Lys also extend beyond the surface, as tyrosine's role in neurotransmitter production
aids in managing stress, which can adversely affect skin health and accelerate aging. This holistic
angle differentiates it from peptides that only address superficial concerns. Despite the broader
benefits of Lys-Tyr-Lys, it is worth noting that the choice of peptides can depend heavily on individual
skincare needs. While some individuals might be better served with peptides targeting specific concerns,
Lys-Tyr-Lys presents a valuable option for those seeking a multi-functional, balanced approach to
skincare.
What makes Lys-Tyr-Lys an effective ingredient in anti-aging
formulations?
Lys-Tyr-Lys has garnered attention as a formidable component in anti-aging
formulations, primarily due to its multifaceted impact on skin health. The anti-aging market demands
ingredients that not only target the visible signs of aging such as wrinkles and fine lines but also
improve the underlying structural integrity of the skin. Lys-Tyr-Lys meets these criteria through its
synergistic blend of amino acids. The dual presence of lysine in Lys-Tyr-Lys amplifies its ability to
stimulate collagen production—a critical factor in maintaining skin elasticity and firmness. Collagen is
a protein that naturally diminishes with age, leading to the formation of wrinkles and sagging skin. By
enhancing collagen synthesis, Lys-Tyr-Lys supports the skin's architectural matrix, helping reduce the
appearance of aging on a structural level. This, coupled with lysine's role in supporting skin barrier
function, ensures that the skin retains moisture better, contributing to a plumper and more youthful
appearance. Tyrosine enhances the tri-peptide's anti-aging efficacy through its role in cellular repair
and regeneration. The amino acid assists in the production of melanin and aids in evening out skin tone,
addressing hyperpigmentation and age spots that commonly appear as skin matures. By ensuring an even
complexion and reducing discoloration, tyrosine adds a vibrant, youthful glow to the skin. Moreover,
Lys-Tyr-Lys’s contribution to neurotransmitter synthesis (courtesy of tyrosine) may indirectly benefit
aging skin. Stress and mood have profound effects on one's physical appearance, including accelerated
skin aging due to hormonal changes and decreased cell turnover. By potentially enhancing mood and
reducing stress impacts through neurotransmitter support, Lys-Tyr-Lys offers an anti-aging advantage
that extends beyond topical application. Overall, the integration of Lys-Tyr-Lys into anti-aging
formulations is supported by its comprehensive approach to maintaining and restoring youthful skin. It
not only focuses on reducing surface-level signs of aging but also bolsters the skin's internal strength
and vitality, helping users achieve a more enduring youthful look.
Are there any known side
effects or considerations when using Lys-Tyr-Lys?
Lys-Tyr-Lys is generally recognized as a safe
and well-tolerated ingredient in skincare and health applications, largely attributed to its natural
amino acid components. However, as with any active ingredient, certain considerations are necessary to
ensure optimal outcomes and user satisfaction. The probability of adverse reactions to Lys-Tyr-Lys is
low, especially when compared to synthetic compounds that may cause irritation or allergic responses.
This is due to its composition of naturally occurring amino acids, which are not foreign to the body.
That said, individual sensitivities can vary, and it's possible for some users to experience mild
irritation or redness when first incorporating the peptide into their regime. Such responses are
generally temporary and subside as the skin acclimates to the new product. Skin type plays a crucial
role in how Lys-Tyr-Lys is tolerated. Sensitive skin types, while generally benefiting from the
peptide’s calming properties, should still conduct a patch test before full application to confirm
compatibility. This can prevent any unforeseen reactions and provide confidence in its incorporation
into daily use. In addition to skin type considerations, the concentration of Lys-Tyr-Lys in
formulations can affect its efficacy and safety. Higher concentrations may provide rapid results but
could increase the risk of irritation, although the peptide's inherently gentle nature helps minimize
this risk. Therefore, beginning with products containing a moderate concentration of Lys-Tyr-Lys is
advisable before gradually increasing potency, thus allowing the skin to adjust without adverse effects.
Another important factor is product formulation. Lys-Tyr-Lys is often combined with other active
ingredients in skincare products, so users should be aware of potential interactions. For those with
specific skin concerns or conditions, such as eczema or rosacea, professional consultation can provide
tailored advice, ensuring that the peptide harmonizes with other components to enhance rather than
compromise skin health. Monitoring skin response is critical when embarking on new skincare treatments.
Users are encouraged to observe how their skin reacts over several weeks to ensure Lys-Tyr-Lys is
performing as desired. This proactive approach can help leverage its benefits while avoiding unnecessary
irritation or discomfort.